Lupane is a district in Matabeleland North Province in Zimbabwe. It lies at a height of 976m. In 2006 it had 1,600 inhabitants. It is on the road from Bulawayo to Hwange. In the years since 2000, there has been nearly 200 cases of torture by the militias of the ZANU-PF. Lupane is a rural, semi-arid area, which cultivates cotton and corn. A new university has been proposed for the district, which would cater for the rest of Mat. north province.
Lupane town is the main centre for the district and is the location of the Matebeleland North government head offices. It also houses the Provincial hospital (under construction).
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